Use of alcohol is a leading cause of morbidity and mortality in adolescents and young adults. Early interventions may reduce the burden associated with alcohol misuse and alcohol related disorders. Screening, Brief Intervention and Referral to Treatment (SBIRT) is a comprehensive and integrated approach to the delivery of early interventions for persons with substance use disorders or at risk for substance use. This paper describes the components, rationale and evidence for the SBIRT approach for people with at risk alcohol use or with alcohol abuse or dependence.